Utilizing Clean Genome Strains for high-yield dsRNA Synthesis
Double-stranded RNA (dsRNA) and small RNAs play an important role in RNA interference (RNAi), a biological process used for gene silencing that holds promise for therapeutic interventions.
Scarab Genomics has advanced dsRNA production by introducing strategic modifications to select Clean Genome E. coli strains. These targeted changes are designed to eliminate non-essential genes and pathways, thereby reducing metabolic burden and enhancing cellular resources available for dsRNA synthesis.
The Clean Genome strains developed by Scarab Genomics represent a significant leap forward in the production of dsRNA and small RNAs. These strains have been meticulously engineered to improve overall efficiency and yield of RNA. The result is a bacterial strain capable of producing dsRNA at levels exceeding 80% of total RNA, see figure.
Collaborating with Scarab Genomics for Scalable dsRNA and small RNA production
Let Scarab Genomics collaborate with you to generate high levels of double-stranded and small RNA while benefiting from the unique advantages of Scarab’s Clean Genome bacterial production strains.
Complete the form below to start the conversation and learn how you can gain access to tailored strains that meet your specific dsRNA production needs.
Learn More
In addition to the strains in our online catalog, we have an extensive library of Clean Genome E. coli strains with various additional genetic modifications. Complete the form below to connect with our team to learn more about the Clean Genome strain for double-stranded and small RNAs, including pricing and licensing options.
Learn More
In addition to the strains in our online catalog, we have an extensive library of Clean Genome E. coli strains with various additional genetic modifications. Complete the form below to connect with our team to learn more about the Clean Genome strain for double-stranded and small RNAs, including pricing and licensing options.